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Kobbie Mainoo will not continue his sensational start to life in the Manchester United first XI as he misses the trip to the London Stadium today.
United will face West Ham without the 18 year old due to illness.
Christian Eriksen is back in the squad and on the bench after a spell on the sidelines.
United’s defence sees the return of Aaron Wan-Bissaka at right back due to Diogo Dalot’s suspension at the hands of Michael “book him Danno” Oliver.
The rest of the defence remains unchanged, with Raphael Varane partnering Jonny Evans at centre back, Luke Shaw at left back and Andre Onana in goal.
Manager Erik ten Hag revealed that Victor Lindelof has undergone surgery and will be out for a month. He joins Harry Maguire, Lisandro Martinez and Tyrell Malacia on the physio’s table. This means that Sergio Reguilon is the only fit backup defender in the entire squad.
In midfield, Mainoo’s absence means Scott McTominay will partner Sofyan Amrabat, with Bruno Fernandes ahead of them. Eriksen will hope to get half an hour from the bench as he works his way back to full fitness.
Casemiro is back in light training but Ten Hag does not expect him back in contention for a start before mid-January.
Donny van de Beek is on the bench despite having agreed a January loan move to Eintracht Frankfurt.
Up front, there is still no place for struggling Marcus Rashford, who is on the bench.
Alejandro Garnacho and Antony keep their places on the left and right wing, respectively, and Rasmus Hojlund will hope to get off the mark up front in his 14th Premier League game.
Kick off at the London Stadium is at 12.30pm GMT.
More to follow …